This paper examines the concept of objectivity traceable in Francis Bacon's natural philosophy. After some historical background on this concept, it considers the question of whether it is not an anachronism to attribute such a concept to Bacon, since the word ‘objectivity’ is a later coinage and does not appear anywhere in his writings. The essay gives reasons for answering this question in the negative, and then criticizes the accounts given of Bacon's understanding of objectivity by Lorraine Daston and (...) class='Hi'>Julie Robin Solomon. It argues that this understanding is most directly and fully expressed in his discussion of the idols of the mind. In this connection, the paper notes Bacon's critical attitude to sixteenth-century scepticism and its relevance to the idea of objectivity implicit in his comments on the idols. In conclusion, the paper argues that Bacon was not a pure empiricist and describes the place assigned to theories and hypotheses in his natural philosophy. (shrink)

D‐amino acids are being recognized as functionally important molecules in mammals. We recently identified endogenous D‐cysteine in mammalian brain. D‐cysteine is present in neonatal brain in substantial amounts (mM) and decreases with postnatal development. D‐cysteine binds to MARCKS and a host of proteins implicated in cell division and neurodevelopmental disorders. D‐cysteine decreases phosphorylation of MARCKS in neural progenitor cells (NPCs) affecting its translocation. D‐cysteine controls NPC proliferation by inhibiting AKT signaling. Exogenous D‐cysteine inhibits AKT phosphorylation at Thr 308 and Ser (...) 473 in NPCs. D‐cysteine treatment of NPCs led to 50% reduction in phosphorylation of Foxo1 at Ser 256 and Foxo3a at Ser 253. We hypothesize that in the developing brain endogenous D‐cysteine is as a physiologic regulator of NPC proliferation by inhibiting AKT signaling mediated by Foxo1 and Foxo3a. Endogenous D‐cysteine may regulate mammalian neurodevelopment with roles in schizophrenia and Alzheimer's disease (AD). (shrink)

Interviewet er lavet i juli 2021. Dets formål er at belyse emner, der er centrale i Celikates’ tænkning, f.eks. den voksende højrefløjspopulisme, migration, voldelige versus ikke-voldelige protester, civil ulydighed og den kritiske filosofis rolle i dag. -/- When Celikates and I sat down digitally in July 2021, the interview’s primary purpose was to examine topics central to Celikates’ thinking, such as the rise of right-wing populism, migration, violent versus non-violent protest, civil disobedience, and the role of critical philosophy today.

New techniques in genome editing have led to a controversial debate about the opportunities and uncertainties they present for agricultural food production and consumption. In July 2018, the Court of Justice of the European Union defined genome editing as a new process of mutagenesis, which implies that the resulting organisms count as genetically modified and are subject, in principle, to the obligations of EU Directive 2001/18/EG. This paper examines how key protagonists from academia, politics, and the economy strategically framed the (...) debate around genome editing in agriculture in Germany prior to its legal classification by the Court of Justice. It is based on an analysis of 96 official statements, including position papers, press releases, and information brochures. Our study reveals eight strategic frames used in the discourse on genome editing and uncovers the strategies used to disconnect from or connect with the previous discourse on green genetic engineering in the 1970s, 1980s and 1990s. Building on competitive framing theory, the study provides explanations for the use and emergence of counter-framing strategies and their success or failure in the debate around genome editing. (shrink)

Here at the Center, we had the privilege of seeing how Dan Callahan lived out his last days and weeks. True to his nature, Dan never stopped thinking or writing. Indeed, his wife Sidney told me that he finished his last essay one day before his death, on July 16th, insisting that she help him get to the computer so he could discuss it with a colleague. “It's my last one,” he told her with his characteristic self‐awareness. Dan also chose (...) the last topic he would focus on: climate change. At a December 2018 board meeting, Dan presented his desire to develop a workshop to explore the ways in which bioethics in general, and The Hastings Center in particular, might be able to make a valuable contribution to addressing the problem of global warming. (shrink)

From the Federal Theater Projects of the Great Depression to the disruptive performances of the 1960s and 1970s, theater has played an important role in American radicalism. This special issue of_ _Theater_ reports on socially conscious, politically active theaters in the United States. Despite the evaporation of Cold War passions and the rise of conservatism in the 1980s and 1990s, such theater work remains a persistent and evolving presence on the political landscape. Since the first inauguration of George W. Bush, (...) new opportunities have arisen for political performance and for significant new challenges to these artists. T_heater and Social Change_ not only tracks the historical evolution of political theater but also explores the current state and future prospects of different modes, including agit-prop, demonstrations, solo performance, Augusto Boal’s Theater of the Oppressed, and community-based production. With such notable contributors as Anna Deavere Smith, Jonathan Kalb, Holly Hughes, and Tony Kushner, the issue offers a diverse assemblage of personal statements, conversations, photographs, interviews, and performance text. _Contributors include:_ Reverend Billy, Jan Cohen-Cruz, Arlene Goldbard, Sharon Green, Lani Guinier, Holly Hughes, Jonathan Kalb, Tony Kushner, Judith Malina, Robbie McCauley, John O'Neal, Claudia Orenstein, Bill Rauch, Julie Salverson, Anna Deavere Smith, Alisa Solomon, Roberta Uno. (shrink)

A commentary on “What's Not Being Shared in Shared Decision‐Making?” from the July‐August 2013 issue.

Le catalogue des Belles Lettres s’est enrichi en 2016 d’une nouvelle traduction de deux œuvres parmi les plus importantes de la philosophie et de la rhétorique, le Gorgias de Platon et l’Éloge d’Hélène de Gorgias, réunies dans un volume unique, accessible, dense, et riche d’un notable travail de synthèse. Cette traduction en langue française rejoint donc celles d’É. Chambry (1912), d’A. Croiset (1923), de L. Robin (1940) et de M. Canto (1987) pour le Gorgias, et celles de J.-L. Poirier (...) (1988)... (shrink)

Robin Downie has distinguished between two enduring cognitive and practical attitudes that have determined the way that doctors and societies thought about medicine. The Hippocratic tradition attached its faith to empirical observation and rational induction and deduction, while the Asklepian approach was holistic, intuitive and strongly spiritual. Hippocrates sought to generalize from individual observations, to generate rules and guidelines from pooled experience. Asklepian physicians believed that cure lay in understanding the personal experience of each patient, and in providing an (...) ambience of healing centered on temples and sacred ground. Hippocratic medicine emphasized the empirical.. (shrink)

An important volume connecting classical studies with feminism, Feminism and Ancient Philosophy provides an even-handed assessment of the ancient philosophers' discussions of women and explains which ancient views can be fruitful for feminist theorizing today. The papers in this anthology range from classical Greek philosophy through the Hellenistic period, with the predominance of essays focusing on topics such as the relation of reason and the emotions, the nature of emotions and desire, and related issues in moral psychology. The volume contains (...) some new, ground-breaking essays on Plato, Aristotle, and the Stoics, as well as previously published pieces by established scholars like Martha Nussbaum and Julia Annas. It promises to be of interest to an interdisciplinary audience including those working in classics, ancient philosophy, and feminist theory. (shrink)

This article discusses what is involved in having full moral status, as opposed to a lesser degree of moral status and surveys different views of the grounds of moral status as well as the arguments for attributing a particular degree of moral status on the basis of those grounds.

In this paper we assess the explanatory role of idealizations in ‘design explanations’, a type of functional explanation used in biology. In design explanations, idealizations highlight which factors make a difference to phenomena to be explained: hypothetical, idealized, organisms are invoked to make salient which traits of extant organisms make a difference to organismal fitness. This result negates the view that idealizations serve only pragmatic benefits, and complements the view that idealizations highlight factors that do not make a difference. This (...) analysis in particular strengthens the perspective that idealizations are means to highlight difference making factors, and identifies a novel, more direct role for idealizations in doing so. It thus offers a novel argument why in some explanatory contexts idealizations are in-eliminable. (shrink)

Corporate Social Responsibility (CSR) programs are increasingly popular corporate marketing strategies. This paper argues that CSR programs can fall along a continuum between two endpoints: Institutionalized programs and Promotional programs. This classification is based on an exploratory study examining the variance of four responses from the consumer stakeholder group toward these two categories of CSR. Institutionalized CSR programs are argued to be most effective at increasing customer loyalty, enhancing attitude toward the company, and decreasing consumer skepticism. Promotional CSR programs are (...) argued to be more effective at generating purchase intent. Ethical and managerial implications of these preliminary findings are discussed. (shrink)

The dominant theory of cross-disciplinarity represents multidisciplinarity as ‘lower’ or ‘less interesting’ than interdisciplinarity. In this paper, it is argued that this unfavorable representation of multidisciplinarity is ungrounded because it is an effect of the theory being incomplete. It is also explained that the unfavorable, ungrounded representation of multidisciplinarity is problematic: when someone adopts the dominant theory of cross-disciplinarity, the unfavorable representation supports the development of a preference for interdisciplinarity over multidisciplinarity. However, being ungrounded, the support the representation provides for (...) a preference for interdisciplinarity, is invalid. The issue is even more pressing because research policy makers and funding bodies are among the adopters of the theory, which means that there is a risk of policies reflecting an unjustified preference for interdisciplinarity over multidisciplinarity. This paper presents an improved version of the dominant theory of cross-disciplinarity, obtained by completing the original version with the information it was missing. Because the improved version is more neutral regarding the value of different types of cross-disciplinarity, it is better suited for use by research policy makers and funding bodies. (shrink)

Overview The debate over the semantics of proper names has, of late, heated up, focusing on the relative merits of referentialism and predicativism. Referentialists maintain that the semantic function of proper names is to designate individuals. They hold that a proper name, as it occurs in a sentence in a context of use, refers to a specific individual that is its referent and has just that individual as its semantic content, its contribution to the proposition expressed by the sentence. Furthermore, (...) a proper name contributes its referent to the proposition expressed by virtue of mechanisms of direct reference to individuals, not by virtue of expressing properties. Predicativists embrace an opposing view according to which proper names are just a special kind of common noun. Their semantic function is to designate properties of individuals. A proper name, as it occurs in a sentence in a context of use, expresses a property, and that property is its contribution to the proposition expr .. (shrink)

The topic of professionalism has dominated the content of major academic medicine publications during the past decade and continues to do so. The message of this current wave of professionalism is that medical educators need to be more attentive to the moral sensibilities of trainees, to their interpersonal and affective dimensions, and to their social conscience, all to the end of skilled, humanistic physicians. Urgent calls to address professionalism from such groups as the Association of American Medical Colleges, the American (...) Board of Internal Medicine, and the Accreditation Council for Graduate Medical Education, among others. In fact, at the 2004 annual meeting of the AAMC six separate presentations addressed professionalism with such titles as "Evaluating Humanism and Professionalism," Professionalism: Expectation, Education, Evaluation," or "Toward Assessing Professional Behaviors of Medical Students through Peer Observations". Professionalism, then, has become part of the current academic medicine parlance, used by administrators, clinical faculty, residency programs, and professional organizations with an expectation of shared meanings and goals. All of these stakeholders focus on what has become a consistent list of attributes deemed to be the essence of professionalism, which usually include variations on altruism, duty, excellence, honor and integrity, accountability, and respect. In fact, most of the scholarly work to date has been listing, describing, decrying, and measuring/evaluating it. In this collection of essays, we don’t argue with these attributes. Instead, we ask questions of the discourse from which they arise, how the specialized language of academic medicine disciplines has defined, organized, contained, and made seemingly immutable a group of attitudes, values, and behaviors subsumed under the label "professional" or "professionalism." This collection aims to be a critical text, one that questions the profession’s beliefs about the nature of its work and how such beliefs are enacted in medical education, particularly as they fuel the professionalism discourse. In addition, we will scrutinize how the discourse is enacted in both the formal and hidden curriculum, and in the larger medical environment. (shrink)

Philosophers of mind and language who advance causal theories face a sort of conjunction problem. When we say that the thing had in mind or the thing referred to is a matter of what causally impacted the thinker or speaker, we must somehow narrow down the long conjunction of items in a causal chain, all of which contributed to the having in mind, but only one of which becomes the object of thought or the linguistic referent. Here, I sketch a (...) notion of cognitive focus intended to do this narrowing. The notion borrows three key aspects from visual focus and some technological aides—causation, amplification, and suppression. I suggest a broader application of this framework to address the conjunction problem not only in ordinary contexts of perceptual focus but also in evidence cases involving non-perceptual cognitive focus. I further suggest cognitive focus is helpful in distinguishing referential vs. attributive thought. (shrink)

The reclamation of slurs raises a host of important questions. Some are linguistic: What are the linguistic conventions governing the slur post-reclamation and how are they related to the conventions governing it pre-reclamation? What mechanisms engender the shift? Others bend toward the social: Why do a slur’s targets have a special privilege in initiating its reclamation? Is there a systematic explanation why prohibitions on out-group use of reclaimed slurs vary from slur to slur? And how does reclamation contribute to shaping (...) social identities and reversing oppressive social norms and stigma? Most analyses of slur reclamation advance a single model to answer these questions. The author argues that there are different varieties of reclamation. Two predominate, what she calls pride reclamation and insular reclamation. While many features unite pride and insular reclamation, they differ with respect to the purpose of the reclamatory act, the linguistic mechanisms reclaimers employ to execute the linguistic change, and the social and grammatical roles of the reclaimed slur. By distinguishing these two types of reclamation and offering a fine-grained characterization of their properties, the author argues that we gain deeper insight into the reasons why slurs may in principle only be ignited by the target group and why pride- but not insular-reclaimed slurs become available for use by out-group members. (shrink)

Wider diversity in board member characteristics has been advocated as a means of improving organizational performance by providing boards with new insights and perspectives. With data from 240 YMCA organizations, a board diversity index was constructed and compared to multiple measures of board member diversity. Results revealed higher levels of social performance and fundraising results when board members had greater occupational diversity. Gender diversity compared favorably to the organization's level of social performance but a negative association surfaced for level of (...) funds raised. The diversity in board member age groupings was linked to higher levels of donations. (shrink)

Behavioral research has revealed how normal human cognitive processes can tend to lead us astray. But do these affect economic researchers, ourselves? This article explores the consequences of stereotyping and confirmation bias using a sample of published articles from the economics literature on gender and risk aversion. The results demonstrate that the supposedly ‘robust’ claim that ‘women are more risk averse than men’ is far less empirically supported than has been claimed. The questions of how these cognitive biases arise and (...) why they have such power are discussed, and methodological practices that may help to attenuate these biases are outlined. (shrink)

In “Moral Luck” Bernard Williams describes a lorry driver who, through no fault of his own, runs over a child, and feels “agent-regret.” I believe that the driver’s feeling is moral since the thought associated with this feeling is a negative moral evaluation of his action. I demonstrate that his action is not morally inadequate with respect his moral obligations. However, I show that his negative evaluation is nevertheless justified since he acted in way that does not live up to (...) his moral values. I then use this distinctive negative moral evaluation to distinguish agent-regret from guilt and mere regret. (shrink)

Background:Research Ethics Committees (RECs) or their equivalent review applications for prospective research with human participants. Reviewers use universally agreed principlesi to make decisions...

The possibilities for collecting, storing, and processing of data have increased significantly over the last decades. It has been argued that an increasing demand for health data will de...

Clarence Sloat, Ora Matushansky, and Delia Graff Fara advocate a Syntactic Rationale on behalf of predicativism, the view that names are predicates in all of their occurrences. Each argues that a set of surprising syntactic data compels us to recognize names as a special variety of count noun. This data set, they say, reveals that names’ interaction with the determiner system differs from that of common count nouns only with respect to the definite article ‘the’. They conclude that this special (...) distribution of names is best explained by the-predicativism, the view that posits the existence of the null-determiner ‘the’ preceding bare singular names. This essay argues that they have incorrectly discerned the syntactic facts: their critical data point concerning the ungrammaticality of sentences like “The Katherine wants coffee” is mistaken. Such sentences’ grammaticality undermines the Syntactic Rationale and presents serious auxiliary problems for predicativism. (shrink)

This paper is the first of two in a series. In this paper, we identify mental health needs and challenges in the age of COVID-19 among Nepali-speaking, Bhutanese resettled refugees in the USA. We argue for a public health justice framework that looks critically at social determinants impacting mental health (SDIMH) barriers, which negatively impact our Bhutanese population, and serves as a theoretical foundation toward public policy and law that will inform healthcare decisions and fair treatment of resettled refugees at (...) the clinical bedside and in the community. We first describe our Bhutanese refugee population and the critical mental health issues that, for many, originated during political persecution and violent ethnic cleansing initiatives, or while living in refugee camps prior to resettlement to the USA. We present a social justice framework emerging from an extensive literature review and incorporating core social determinants specific to mental health in the age of COVID-19, which are guided by the social determinants of economic stability; neighborhoods and physical environment; education; nutrition and exercise; community and social context; healthcare system; and legal system. We illustrate specific SDIMH of our resettled Bhutanese refugees during the pandemic, followed by a second paper that details recommendations for applying the SDIMH in a collective effort to address specific barriers to mental healthcare and support. (shrink)

Theories of slurs aim to explain how – via semantics, pragmatics, or other mechanisms – speakers who use slurs convey that targets are inferior persons. I present two novel problems. The Slur Creation Problem: How do terms come to be slurs? An expression ‘e’ is introduced into the language. What are the mechanisms by which ‘e’ comes to possess properties distinctive of slurs? The Bigotry Formation Problem: Speakers’ uses of slurs are a prime mechanism of bigotry formation, not solely bigotry (...) perpetuation. With a use of a slur, how are speakers able to introduce new bigoted attitudes and actions toward targets? I argue that expressivism offers powerful resources to solve the problems. (shrink)

Building upon the foundations laid by Russell, Donnellan, Chastain, and more recently, Almog, this paper addresses key questions about the basic mechanism by which we think of worldly objects, and (in contrast to many connected projects), does so in isolation from questions about how we speak of them. I outline and defend a view based on the notion of bound cognition. Bound cognition, like perception, is world-to-mind in the sense that it is generated by the item being thought of rather (...) than by the mind doing the thinking. It is a direct, two-place, non-representational relation, and it is prior to any epistemic connection between the thinker and the object of thought. Although the paradigm case for bound cognition involves sensory perception of an individual, I argue that the cognitive relations falling under the heading of bound cognition also include non-perceptual cognitive relations (such as the relation between a thinker and a historical individual) as well as cognitive relations to non-individuals (such as pairs, pluralities, species, and features). Four illustrative cases are discussed, and anticipated worries about abstract and empty cases are addressed. (shrink)

Quotation has been much studied in philosophy. Given that quotation allows one to diagonalize out of any grammar, there have been comparatively few attempts within the linguistic literature to develop an account within a formal linguistic theory. Nonetheless, given the ubiquity of quotation in natural language, linguists need to explicate the formal mechanisms it employs. The central claim of this paper is that once one assumes a dialogical perspective on language such as provided by the KoS (KoS is not an (...) acronym, despite emphasizing a Konversationally Oriented Semantics) framework, formalized in a rich type theory like Type Theory with Records, much of the mystery evaporates. In particular, one can utilize as denotations for quotative constructions entities that are independently motivated for dialogue processing—utterance types and locutionary propositions, Austinian propositions about speech events. (shrink)